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Pearson Edexcel · International GCSE · Biology

  • 1

    1 · The nature and variety of living organisms

    Chương trình học sắp ra mắt

    Tài liệu

    English

    What counts as alive?

    A housefly and a maize plant could not look more different, yet both are alive in the same eight ways, and both are built from the same kind of cell. This first section gives you the words for that shared life — the characteristics every organism shows — and a map of life's variety: five groups of organisms plus the viruses, which are not alive at all but still infect every living thing.

    Edexcel International GCSE Biology 4BI1, Section 1 is assessed in both papers; expect direct recall and "compare" questions from 1.1–1.4, often one mark for a feature and one for the named example.

    The characteristics of life

    Every living organism does all eight: it takes in nutrition 营养 (material for energy or growth), it respires 呼吸 (releases energy from food), it excretes 排泄 (removes waste), it responds 反应 to its surroundings, it moves 运动, it controls its internal conditions (keeps itself steady inside), it reproduces 繁殖, and it grows and develops 生长. The memory hook MRS GREN lists movement, reproduction, sensitivity, growth, respiration, excretion, nutrition — the "control of internal conditions" is the eighth that the hook leaves out, so name it separately.

    A virus does none of these by itself — that is why it is not living.

    Variety: the five groups and their give-away features

    Plants 植物: multicellular; cells contain chloroplasts 叶绿体 and carry out photosynthesis 光合作用; walls of cellulose 纤维素; carbohydrate stored as starch 淀粉 or sucrose. Examples: a cereal (maize) and a herbaceous legume (peas or beans).

    Animals 动物: multicellular; no chloroplasts, no photosynthesis; no cell walls; usually nervous coordination and movement from place to another; store carbohydrate as glycogen 糖原. Examples: mammals (humans) and insects (housefly, mosquito).

    Fungi 真菌: no photosynthesis; body usually a mycelium 菌丝体 of thread-like hyphae 菌丝 containing many nuclei; some single-celled (yeast); walls of chitin 几丁质; feed by secreting digestive enzymes onto food outside the body and absorbing the products — saprotrophic nutrition 腐生营养; store glycogen. Examples: Mucor (typical hyphae) and yeast 酵母 (single-celled).

    Protoctists 原生生物: microscopic single-celled organisms. Amoeba (pond water) is like an animal cell; Chlorella has chloroplasts and is like a plant. The pathogenic example is Plasmodium, which causes malaria 疟疾.

    Bacteria 细菌: microscopic single-celled organisms with a cell wall, cell membrane, cytoplasm and plasmids 质粒; they lack a nucleus but have a circular chromosome of DNA 环状DNA. Some photosynthesise; most feed off living or dead organisms. Examples: Lactobacillus bulgaricus (rod-shaped, used to make yoghurt) and Pneumococcus (spherical, causes pneumonia 肺炎).

    One panel per group with the features to recall and a named example for each.

    The four-way comparison the examiners like: cell wall material (cellulose / none / chitin / bacterial wall), nucleus (yes / yes / yes / no), chloroplasts (plants and some protoctists only), storage carbohydrate (starch / glycogen / glycogen / —).

    Pathogens and the viruses

    A pathogen 病原体 is any organism or particle that causes disease — the specification allows fungi, bacteria, protoctists or viruses.

    Viruses 病毒 are not living organisms: they are small particles (smaller than bacteria), parasitic, and can reproduce only inside living cells; they have no cellular structure — just a protein coat 蛋白质外壳 containing one type of nucleic acid, DNA or RNA (never both). Learn the three named examples with their diseases: tobacco mosaic virus 烟草花叶病毒 (discoloured tobacco leaves — it stops chloroplasts forming), influenza virus 流感病毒 (flu) and HIV 艾滋病毒 (AIDS).

    Approximate sizes: a virus is far smaller than a bacterium, which is far smaller than a plant or animal cell.

    Check yourself

    1. List the eight characteristics shared by all living organisms.
    2. Give two features of a plant cell that an animal cell lacks.
    3. Which group stores carbohydrate as glycogen, and which as starch?
    4. Describe saprotrophic nutrition in fungi, using the words hyphae, enzymes and absorb.
    5. How does the genetic material of a bacterium differ from that of a plant cell?
    6. Name the pathogenic protoctist and the disease it causes.
    7. State three reasons why viruses are not classified as living organisms.
    8. Which named virus prevents chloroplast formation, and what is the visible result?

    Answers: 1 nutrition, respiration, excretion, response, movement, control of internal conditions, reproduction, growth; 2 chloroplasts and a cellulose cell wall; 3 animals and fungi store glycogen; plants store starch (or sucrose); 4 fungi secrete digestive enzymes from their hyphae onto dead food material, then absorb the soluble organic products; 5 a bacterium has no nucleus — circular DNA chromosome plus plasmids — while a plant cell keeps its DNA in a nucleus; 6 Plasmodium — malaria; 7 no cellular structure; reproduce only inside living cells; no life processes alone; 8 tobacco mosaic virus — discoloured, mosaic-patterned leaves.

    Từ vựng
    English Tiếng Việt
    nutrition/njuːˈtrɪʃn/ dinh dưỡng
    respiration/ˌrespɪˈreɪʃn/ hô hấp
    excretion/ekˈskreʃn/ thải tiết
    respond/rɪˈspɒnd/ phản ứng
    movement/ˈmuːvmənt/ chuyển động
    reproduce/rɪprəˈdjuːs/ sinh sản
    grow sinh trưởng
    photosynthesis/ˌfəʊtəʊˈsɪnθəsɪs/ quang hợp
    plants thực vật
    chloroplast/ˈklɔːrəʊplæst/ lạp chloroplast
    cellulose/ˈseljuːləʊs/ cellulose
    starch/stɑːtʃ/ tinh bột
    animals động vật
    glycogen/ˈɡlaɪkədʒn/ glycogen
    fungi/ˈfʌŋɡi/ nấm
    mycelium mycelium
    hyphae hyphae
    chitin chitin
    saprotrophic nutrition dưỡng chất dị dưỡng
    yeast/jiːst/ men
    protoctists/ˈprəʊtəʊktɪsts/ protoctists
    malaria/mæˈleərɪə/ sốt rét
    bacteria/bækˈtɪərɪə/ vi khuẩn
    plasmids/ˈplæzmɪdz/ plasmids
    circular DNA DNA vòng
    pneumonia viêm phổi
    viruses/ˈvaɪrəsɪz/ virus
    pathogen/ˈpæθədʒn/ mầm bệnh
    protein coat/ˈprəʊtiːn kəʊt/ vỏ protein
    tobacco mosaic virus/təˈbækəʊ məˈseɪɪk ˈvaɪrəs/ virus khảm thuốc lá
    influenza virus Virus cúm
    HIV/ˌeɪtʃ aɪ ˈviː/ Virus HIV
  • 2

    2 · Structures and functions in living organisms

    Chương trình học sắp ra mắt

    Tài liệu

    English

    From cell to system

    One cell became many; many cells became tissues, organs and systems; and every system serves the same three jobs — taking in what the body needs, moving it to where it is used, and removing what the body must not keep. This section is the core of IGCSE Biology: cells and molecules, how substances cross membranes, nutrition in plants and humans, respiration, gas exchange, transport, excretion and coordination.

    Edexcel International GCSE Biology 4BI1, Section 2 (statements 2.1–2.95) is the largest section of the course and feeds every long question on both papers. B-suffixed statements are the separate-science (Biology-only) extension; double-award students learn the unlettered core.

    Organisation and cells

    Organisation runs upward: organelles 细胞器 → cells 细胞 → tissues 组织 → organs 器官 → systems 系统.

    A plant cell with cellulose wall, chloroplasts and vacuole beside an animal cell with neither.
    Structure Function
    Nucleus contains DNA, controls the cell
    Cytoplasm where reactions happen
    Cell membrane controls what enters and leaves
    Cell wall (plants) strength (cellulose)
    Mitochondria release energy in respiration
    Chloroplasts (plants) absorb light for photosynthesis
    Ribosomes protein synthesis
    Vacuole stores water and dissolved substances (large and permanent in plants)

    2.5B Specialised cells develop by cell differentiation 细胞分化; 2.6B stem cells can replace damaged cells — advantages: treat conditions like paralysis or leukaemia; disadvantages: ethical concerns over embryos, risk of rejection and uncontrolled division.

    Biological molecules and enzymes

    Carbohydrates contain C, H, O; proteins add N; lipids are C, H, O with much less oxygen. Large molecules are chains of small units: starch and glycogen from simple sugars, protein from amino acids, lipid from fatty acids and glycerol. 2.9 Food tests: glucose — Benedict's (heated, blue → brick red); starch — iodine (yellow-brown → blue-black); protein — Biuret (blue → purple); fat — ethanol emulsion (cloudy white layer).

    Enzymes 酶 are biological catalysts 生物催化剂: they speed metabolic reactions without being used up. Each has an active site 活性部位 the substrate must fit. Above an optimum temperature or away from the optimum pH, the active site changes shape (denaturation 变性) and the enzyme no longer works. Practical 2.12/2.14B follow amylase digesting starch at different temperatures or pH with iodine.

    Movement into and out of cells

    Diffusion, osmosis and active transport summarised; only active transport needs energy.

    Diffusion 扩散 is the net movement of particles from a higher to a lower concentration (oxygen into blood). Osmosis 渗透 is the diffusion of water across a partially permeable membrane from a dilute to a more concentrated solution. Active transport 主动运输 moves substances against the gradient using energy from respiration (mineral ions into root hair cells). Rate increases with surface-area-to-volume ratio, concentration gradient and temperature, and decreases with distance.

    Nutrition

    Flowering plants. Photosynthesis converts light energy into chemical energy stored in glucose:

    $$6\mathrm{CO_2} + 6\mathrm{H_2O} \xrightarrow{\text{light, chlorophyll}} \mathrm{C_6H_{12}O_6} + 6\mathrm{O_2}$$

    Limiting factors: carbon dioxide concentration, light intensity, temperature — each raises rate until another factor limits. Magnesium ions build chlorophyll (deficiency yellows leaves); nitrate ions build amino acids. 2.23: pondweed shows oxygen evolution; iodine tests a leaf for starch after blocking light, CO₂ or chlorophyll.

    Leaf cross-section with palisade layer rich in chloroplasts and stomata below.

    Humans. A balanced diet: carbohydrate, protein, lipid, vitamins A (night vision), C (connective tissue), D (calcium absorption), calcium (bones) and iron (haemoglobin), water, and dietary fibre. Energy needs rise with activity, growth (age) and pregnancy. The alimentary canal — mouth → oesophagus → stomach → duodenum and ileum → colon and rectum, with the pancreas supplying enzymes — moves food by peristalsis 蠕动. Digestion: amylase and maltase (starch → glucose), proteases (protein → amino acids), lipases (lipid → fatty acids + glycerol). Bile (made in the liver, stored in the gall bladder) neutralises stomach acid and emulsifies lipids into droplets. The ileum's wall is folded into villi 绒毛: huge surface area, one-cell-thick walls, dense capillary network — built for absorption.

    Respiration and gas exchange

    Respiration releases energy from glucose to make ATP, which supplies energy for muscle contraction, protein synthesis and active transport. Aerobic: glucose + oxygen → carbon dioxide + water (symbol equation: C₆H₁₂O₆ + 6O₂ → 6CO₂ + 6H₂O). Anaerobic (without oxygen): in animals glucose → lactic acid (less energy, oxygen debt); in plants and yeast glucose → ethanol + carbon dioxide.

    Plants (2.40B–2.45B). Gases move by diffusion through stomata; the leaf's flat shape, air spaces and thin, moist surfaces serve gas exchange as they serve photosynthesis. By day, photosynthesis outweighs respiration, so the net exchange is CO₂ in and O₂ out; at night only respiration continues (net O₂ in, CO₂ out). Hydrogen-carbonate indicator shows this: orange → yellow with CO₂ (dark), orange → purple with less CO₂ (bright light).

    Humans (2.46–2.50). The thorax: ribs, intercostal muscles, diaphragm, trachea → bronchi → bronchioles → alveoli, all in pleural membranes. Inhaling: intercostal muscles and diaphragm contract, the chest volume rises, pressure falls and air flows in. Smoking damages alveoli (emphysema), clogs arteries and raises coronary heart disease risk.

    An alveolus with a one-cell-thick wall against a capillary: oxygen diffuses in, carbon dioxide out.

    Transport

    Unicellular organisms manage with diffusion alone — every part is close to the surface. Multicellular organisms need transport systems.

    Plants. Xylem transports water and mineral ions from roots to leaves; phloem carries sucrose and amino acids between leaves and the rest of the plant. B-extension: root hair cells absorb water by osmosis; transpiration 蒸腾作用 is the evaporation of water from surfaces, mostly via stomata, faster in low humidity, high wind, high temperature and bright light.

    Humans. Blood: plasma (carries CO₂, digested food, urea, hormones, heat), red blood cells (biconcave discs, no nucleus, full of haemoglobin 血红蛋白 — a large surface and short diffusion path for oxygen), white blood cells (phagocytes ingest pathogens; lymphocytes release specific antibodies), and platelets (clotting, B-extension; vaccination builds memory cells, B-extension).

    The four chambers of the heart with the vessels to and from lungs and body; the left ventricle has the thickest wall.

    The heart's right side pumps blood to the lungs, the left side to the body; exercise and adrenaline raise heart rate. Arteries carry blood away at high pressure (thick, elastic walls), veins return it at low pressure (wide lumen, valves), capillaries exchange materials (one-cell-thick walls). Risk factors for coronary heart disease include smoking, high-fat diet and lack of exercise.

    Excretion

    Plants lose waste O₂ and CO₂ through stomata. Humans excrete CO₂ (lungs), urea + water + ions (kidneys — water and urea also in sweat). B-extension: the kidney filters blood in nephrons (Bowman's capsule → glomerulus; ultrafiltration; selective reabsorption of all glucose at the proximal convoluted tubule; water reabsorbed from the collecting duct under ADH — osmoregulation). Urine holds water, urea and ions; the urinary system runs kidneys → ureters → bladder → urethra.

    Coordination and response

    Homeostasis 稳态 keeps the internal environment constant (water content, temperature). A coordinated response needs stimulus → receptor → effector. Plants respond to light (phototropism 向光性) and gravity (geotropism) — shoots grow towards light, roots downwards — controlled by auxin 生长素 accumulating on the shaded side of a shoot.

    Nervous control is electrical, fast and short-lived; hormonal control is chemical in the blood, slower and longer-lasting. The CNS (brain and spinal cord) links to sense organs by nerves; at a synapse 突触 a neurotransmitter 神经递质 passes the signal between neurones.

    The reflex arc from stimulus to effector, through sensory neurone, relay neurone in the CNS and motor neurone.

    The eye focuses by changing lens shape (near: more curved) and responds to light via the pupil. Skin temperature control: sweating cools by evaporation; vasodilation loses heat; vasoconstriction conserves it. Hormones: adrenaline (adrenal glands — fight or flight), insulin (pancreas — lowers blood glucose), testosterone (testes), progesterone and oestrogen (ovaries); B-extension adds ADH (pituitary), FSH and LH (pituitary — menstrual cycle).

    Check yourself

    1. Put in order of size: cell, organ, organelle, system, tissue.
    2. Give two structures a plant cell has that an animal cell lacks, and one the animal cell has that most plant cells lack many of.
    3. Name the small units that build proteins, starch and lipids.
    4. State the colour changes for Benedict's, iodine and Biuret tests.
    5. Why does heating an enzyme far above its optimum stop it working?
    6. Distinguish diffusion, osmosis and active transport in one sentence each.
    7. Write the balanced symbol equation for photosynthesis and for aerobic respiration.
    8. Give two adaptations of the leaf for photosynthesis and two of the alveolus for gas exchange.
    9. Why can a single-celled organism survive without a transport system?
    10. Compare arteries, veins and capillaries by wall thickness, lumen size and function.
    11. Outline what happens to glucose, water and urea as liquid passes along a nephron (B).
    12. State the pathway of a reflex arc, and give one advantage of reflexes.

    Answers: 1 organelle → cell → tissue → organ → system; 2 cellulose wall and chloroplasts (and a large permanent vacuole); animal cells contain many mitochondria; 3 amino acids; simple sugars; fatty acids and glycerol; 4 Benedict's blue → brick red (with glucose, heated); iodine yellow-brown → blue-black (with starch); Biuret blue → purple (with protein); 5 the active site changes shape (denaturation) so the substrate no longer fits; 6 diffusion — net movement down a concentration gradient; osmosis — water only, across a partially permeable membrane; active transport — against the gradient, using energy; 7 6CO₂ + 6H₂O → C₆H₁₂O₆ + 6O₂ (light, chlorophyll); C₆H₁₂O₆ + 6O₂ → 6CO₂ + 6H₂O; 8 leaf: broad flat surface and palisade cells packed with chloroplasts (or air spaces/stomata); alveolus: one-cell-thin walls and enormous surface area (moist surface, capillary network); 9 its surface area is large compared with its volume, so diffusion reaches every part quickly enough; 10 arteries — thick muscular walls, narrow lumen, carry blood away at high pressure; veins — thin walls, wide lumen, valves, return blood at low pressure; capillaries — one-cell-thick walls, exchange materials; 11 (B) all glucose is selectively reabsorbed into the blood at the proximal convoluted tubule; water is reabsorbed from the collecting duct (controlled by ADH); urea is not reabsorbed and leaves in the urine with water and ions; 12 stimulus → receptor → sensory neurone → relay neurone (CNS) → motor neurone → effector; reflexes are rapid and automatic, protecting the body before harm is done.

    Từ vựng
    English Tiếng Việt
    organelle/ˌɔːɡəˈnel/ Lưỡng bào
    cell/sel/ tế bào
    tissue/ˈtɪʃuː/ 作为
    organ/ˈɔːɡən/ Tổ chức
    system/ˈsɪstəm/ Cơ quan
    cell differentiation Hệ thống
    enzyme/ˈenzaɪm/ enzyme
    biological catalyst Biện phân hóa tế bào
    active site/ˈæktɪv saɪt/ Xúc tác sinh học
    denaturation/ˌdenətʃəˈreɪʃn/ biến tính
    diffusion/dɪˈfjuːʒn/ Vị trí hoạt động
    osmosis/ɒzˈməʊsɪs/ thẩm thấu
    active transport/ˈæktɪv ˈtrænspɔːt/ Khuếch tán
    peristalsis/ˌperɪˈstælsɪs/ Vận chuyển chủ động
    villi/ˈvɪlaɪ/ Co bóp
    transpiration/trænspəˈreɪʃn/ Lông hấp thu
    haemoglobin/ˌhiːməˈɡləʊbɪn/ Thoát hơi nước
    homeostasis/ˌhəʊmiːəˈstɑːsiz/ thống homeostasis
    synapse/ˈsɪnæps/ Huyết sắc tố
    neurotransmitter/ˈnjuːrətrænsmɪtə/ Khớp thần kinh
    auxin/ˈɔːksɪn/ Neurotransmitter
    phototropism/ˌfəʊtəʊˈtrəʊpɪzəm/ Auxin
  • 3

    3 · Reproduction and inheritance

    Chương trình học sắp ra mắt

    Tài liệu

    Truyền đạt lại

    Mỗi sinh vật sống chỉ có một cơ hội để truyền gen của mình lại. Hoa thực hiện điều này thông qua cánh hoa và phấn hoa, con người thông qua giao tử và chu kỳ hormone — và các gói thông tin được truyền tải là nhiễm sắc thể, bị xáo trộn qua giảm phân và tái tổ hợp tại thụ tinh. Phần này bao gồm từ cấu trúc hoa đến phép lai đơn, từ chim Darwin đến vi khuẩn kháng kháng sinh.

    Edexcel International GCSE Biology 4BI1, Section 3 (statements 3.1–3.39) là phần di truyền và sinh sản. Các phép lai và phả đồ mang điểm số đáng tin cậy cho học sinh biết trình bày sơ đồ di truyền đúng cách.

    Sinh sản

    Sinh sản hữu tính cần hai giao tử; con cái khác nhau về mặt di truyền. Sinh sản vô tính cần một bố mẹ; con cái là bản sao giống hệt nhau về mặt di truyền.

    Thực vật có hoa. Hoa thụ phấn nhờ côn trùng có cánh hoa to màu sắc, mùi thơm và mật hoa; hoa thụ phấn nhờ gió nhỏ và màu xanh, có hạt phấn nhẹ và mịn với số lượng khổng lồ, nhị treo bên ngoài và nhụy lông vũ.

    So sánh đặc điểm của hoa thụ phấn nhờ côn trùng và thụ phấn nhờ gió.

    Sau khi thụ phấn, hạt phấn mọc một ống phấn xuống đầu nhụy; thụ tinh xảy ra sau đó, và noãn trở thành hạt trong khi bầu nhụy trở thành quả. Hạt đang nảy mầm sống dựa vào dự trữ thức ăn đã lưu trữ cho đến khi cây con có thể quang hợp. Thực vật sinh sản vô tính bằng cành bò và nhân tạo bằng giâm cành.

    Con người. Chu kỳ kinh nguyệt: FSH làm trưởng thành trứng trong buồng trứng; nang noãn trưởng thành giải phóng oestradiol, làm dày niêm mạc tử cung và kích thích sóng LH gây ra rối loạn rụng trứng vào khoảng ngày 14; nang trống trở thành thể vàng giải phóng progesterone, giữ niêm mạc dày cho đến ngày 28, khi mức hormone giảm dẫn đến kinh nguyệt (B: FSH và LH từ tuyến yên).

    Bốn hormone của một chu kỳ: FSH sớm, sóng LH tại thời điểm rụng trứng, oestradiol sau đó progesterone xuyên suốt nửa sau.

    Placenta cung cấp oxy và dinh dưỡng cho phôi thai và loại bỏ chất thải; dịch ối bảo vệ nó. Oestradiol và testosterone thúc đẩy sự phát triển của đặc điểm giới tính thứ cấp.

    Kế thừa

    Genome là tất cả DNA của một sinh vật; gen là một đoạn phân tử DNA mã hóa cho một protein. Gen nằm trên nhiễm sắc thể trong nhân tế bào. (B) DNA là xoắn kép với các cặp base — A–T và C–G; RNA là chuỗi đơn với U thay thế T. (B) Tổng hợp protein: transcription sao chép gen sang mRNA trong nhân; translation tại ribosome đọc codon, mỗi codon được ghép đôi bởi tRNA anticodon mang axit amin tương ứng, xây dựng chuỗi.

    Tổng hợp protein trong bốn khung: DNA, phiên mã thành mRNA, mRNA đến ribosome, dịch mã thành chuỗi protein.

    Allele là các dạng thay thế của một gen. Từ vựng: trội (hiện ra khi có một bản sao), lặn (cần hai bản sao), thuận hợp, bất thuận hợp, kiểu gen, kiểu hình; (B) đồng trội — cả hai allele đều biểu hiện. Hầu hết đặc điểm là đa gen, không phải do một gen đơn lẻ.

    Phép lai monohybrid, trình bày để đạt điểm tối đa: kiểu gen bố mẹ → giao tử → bảng Punnett → tỷ lệ kiểu hình.

    Ví dụ minh họa. Xơ nang (cf, lặn): cả hai bố mẹ đều bất thuận hợp Cc × Cc. Giao tử C hoặc c. Con cái CC, Cc, Cc, cc — 3 không mắc bệnh : 1 mắc bệnh; xác suất 1 trên 4 cho mỗi đứa trẻ, xác suất như nhau với mọi đứa trẻ.

    Xác định giới tính: XX nữ, XY nam. Mẹ luôn truyền X; bố truyền X hoặc Y — sơ đồ di truyền X×X, X×Y cho giao tử 1:1 nữ:nam, và giao tử của bố quyết định giới tính.

    的伟大分裂 tạo ra hai tế bào có nhiễm sắc thể giống hệt nhau — phát triển, sửa chữa, nhân giống vô tính. 的伟大 phân li tạo ra bốn giao tử nửa bộ khác nhau về mặt di truyền (người lưỡng bội 46 → nửa bộ 23), và thụ tinh ngẫu nhiên giữa bất kỳ tinh trùng nào với trứng nào tạo thêm biến dị.

    的伟大分裂 tạo ra hai tế bào lưỡng bộ giống hệt nhau;的伟大 phân li tạo ra bốn giao tử nửa bộ khác nhau. Biến dị có thể là di truyền, môi trường, hoặc cả hai. Đột biến là sự thay đổi ngẫu nhiên, hiếm gặp trong DNA có thể di truyền — chủ yếu vô hại, đôi khi có ý nghĩa quan trọng (B: một base bị thay đổi có thể làm thay đổi một axit amin và hình dạng protein); bức xạ ion hóa và chất gây đột biến hóa học như hóa chất thuốc lá làm tăng tốc độ đột biến.

    Tiến hóa

    Sự chọn lọc tự nhiên của Darwin, từng bước: sinh vật sinh con nhiều hơn số lượng sống sót; biến dị tồn tại trong một loài; những cá thể có đặc điểm phù hợp nhất với môi trường sống sót và sinh sản, truyền lại allele; qua nhiều thế hệ, đặc điểm có lợi trở nên phổ biến hơn.

    Kháng sinh là sự chọn lọc đang diễn ra: đột biến ngẫu nhiên làm cho một vi khuẩn kháng được; kháng sinh tiêu diệt phần lớn vi khuẩn không kháng; vi khuẩn kháng sống sót và sinh sản — hoàn thành đầy đủ liệu trình kháng sinh và tránh lạm dụng sẽ làm chậm sự lây lan, và các nhiễm trùng kháng sinh trở nên khó kiểm soát.

    Tự kiểm tra

    1. Nêu hai điểm khác biệt giữa sinh sản hữu tính và vô tính.
    2. Nêu hai đặc điểm thích nghi của hoa thụ phấn nhờ gió.
    3. Sau khi ống phấn tiếp cận noãn thì xảy ra gì?
    4. Hormone nào tăng vọt vào ngày 14, và nó gây ra điều gì?
    5. Định nghĩa gen, allele và bộ gen.
    6. (B) Tên base thay thế thymine trong RNA, và nơi diễn ra quá trình dịch mã.
    7. Phép lai Cc × cc và đưa ra tỷ lệ kiểu hình.
    8. Tại sao giao tử của bố quyết định giới tính của đứa trẻ?
    9. Nêu hai điểm khác biệt giữa的伟大分裂 và的伟大 phân li.
    10. Giải thích sự kháng sinh bằng chọn lọc tự nhiên trong ba bước.

    Đáp án: 1 hữu tính — hai bố mẹ, con cái khác nhau về mặt di truyền; vô tính — một bố mẹ, con cái giống hệt nhau về mặt di truyền; 2 hạt phấn nhẹ, trơn, số lượng lớn; bao phấn treo bên ngoài hoa với柱头 lông vũ (cánh hoa nhỏ, tụt màu, không mật); 3 giao tử đực fuse với tế bào trứng của noãn — thụ tinh; noãn trở thành hạt và bầu nhụy thành quả; 4 LH — rụng trứng (phóng thích trứng); 5 gen — một đoạn DNA mã hóa cho một protein; allele — một dạng thay thế của gen; bộ gen — toàn bộ DNA của sinh vật; 6 (B) uracil; tại ribosome; 7 giao tử C, c và c, c → Cc, Cc, cc, cc — 1 không mắc bệnh : 1 mắc bệnh; 8 trứng của mẹ luôn mang X; tinh trùng mang X hoặc Y, vì vậy XX (nữ) hay XY (nam) phụ thuộc vào tinh trùng; 9的伟大分裂 — hai tế bào, giống hệt nhau, cùng (lưỡng bộ) số lượng nhiễm sắc thể, cho phát triển/sửa chữa/nhân giống vô tính;的伟大 phân li — bốn tế bào, khác nhau về mặt di truyền, một nửa số lượng (nửa bộ), cho giao tử; 10 đột biến tạo ra khả năng kháng cho một vi khuẩn; kháng sinh tiêu diệt các vi khuẩn không kháng; vi khuẩn kháng sống sót và sinh sản, do đó khả năng kháng lây lan.

    Từ vựng
    English Tiếng Việt
    pollination/ˌpɒlɪˈneɪʃn/ Hướng sáng
    fertilisation/ˌfɜːtɪlaɪˈzeɪʃn/ thụ tinh
    pollen tube/ˈpɒlən tjuːb/ ống phấn
    FSH/ˌef es ˈeɪtʃ/ hormone kích thích nang noãn (FSH)
    progesterone/prəʊˈdʒestərəʊn/ progesterone
    testosterone/teˈstɒstərəʊn/ testosterone
    genome/ˈdʒiːnəʊm/ bộ gen
    allele/əˈliːl/ alen
    dominant/ˈdɒmɪnənt/ trội
    recessive/rɪˈsesɪv/ lặn
    homozygous/ˌhɒməˈzɪɡəs/ thuần hợp
    heterozygous/ˌhetrəˈzɪɡəs/ dị hợp
    genotype/ˈdʒenətaɪp/ kiểu gen
    phenotype/ˈfenətaɪp/ kiểu hình
    codominance/ˈkəʊdəmɪnəns/ đồng trội
    double helix/ˈdʌbl ˈhiːlɪks/ xoắn kép
    transcription/trænˈskrɪpʃn/ phiên mã
    translation/trænˈsleɪʃn/ dịch mã
    codon/ˈkəʊdɒn/ bộ ba mã hóa
    mitosis/maɪˈtəʊsɪs/ nguyên phân
    meiosis/meɪˈəʊsɪs/ giảm phân
    haploid/ˈhæplɔɪd/ nhiễm sắc đơn bộ
    mutation/mjuːˈteɪʃn/ đột biến
    natural selection/ˈnætʃərəl sɪˈlekʃn/ Lựa chọn tự nhiên
    oestrogen/ˈiːstrədʒn/ Estrogen
  • 4

    4 · Ecology and the environment

    Chương trình học sắp ra mắt

    Tài liệu

    English

    Who lives where, and what eats whom

    A pond holds more than water: populations that feed each other, cycle carbon and nitrogen, and respond — sometimes catastrophically — to what humans add. Ecology asks four questions: who lives here (population, community, habitat, ecosystem), who eats whom (food chains, webs, pyramids), what goes round (the carbon and nitrogen cycles), and what we are doing to it (pollution, greenhouse gases, eutrophication, deforestation).

    Edexcel International GCSE Biology 4BI1, Section 4 (statements 4.1–4.18B) rewards precise definitions and the carbon cycle drawn from memory.

    The organism in the environment

    A population 种群 is all the organisms of one species in a habitat; a community 群落 is all the populations in that habitat; a habitat 栖息地 is the place; an ecosystem 生态系统 is the community plus its non-living surroundings. Population size is set by abiotic 非生物 factors (light, water, temperature) and biotic 生物 factors (food, predators, disease, competition). Quadrat practicals estimate population size (mean per quadrat × total area ÷ quadrat area), and (B) quadrats along a transect show distribution and biodiversity 生物多样性.

    Feeding relationships

    Producers 生产者 (plants) capture light energy; primary consumers 初级消费者 eat producers; secondary and tertiary consumers follow; decomposers 分解者 break down dead material. Arrows in a food chain point from eaten to eater — the direction energy flows. Pyramids of number can invert (one tree, many insects), but pyramids of biomass and of energy transfer always narrow upward — because only about 10 % of the energy at one level passes to the next: the rest is lost in respiration, movement and excretion, and as heat.

    A pyramid of biomass: each level carries about a tenth of the one below it.

    Cycles within ecosystems

    The carbon cycle: photosynthesis and feeding move carbon up, respiration and decomposition return it, combustion of fossil fuels releases stored carbon.

    Carbon: photosynthesis removes CO₂ from the air; feeding passes carbon along chains; respiration 呼吸 (all organisms) and decomposition 分解 return it; combustion 燃烧 of fossil fuels releases carbon stored for millions of years.

    (B) Nitrogen: nitrogen-fixing bacteria make nitrogen compounds from atmospheric N₂; decomposers break dead matter into ammonia; nitrifying bacteria convert ammonia to nitrates plants absorb; denitrifying bacteria return nitrogen to the air.

    Human influences

    Air pollution: sulfur dioxide dissolves in rain to form acid rain (damages leaves, lakes, buildings); carbon monoxide binds haemoglobin, cutting the oxygen blood can carry. Greenhouse gases 温室气体 — water vapour, carbon dioxide, nitrous oxide, methane and CFCs — trap outgoing radiation; burning fossil fuels, deforestation, agriculture and industry add them, thickening the blanket (the enhanced greenhouse effect), bringing global warming with rising sea levels and shifting climates. Sewage in water feeds microbes that consume oxygen. Eutrophication 富营养化: fertiliser leaches into water, algae bloom, die, and decomposers strip the oxygen — fish suffocate.

    The eutrophication sequence from leached fertiliser to oxygen-starved fish.

    (B) Deforestation removes roots and canopy: rain leaches soil minerals away, soil erodes, evapotranspiration falls (less cloud and rain), and stored carbon returns to the air, unbalancing atmospheric gases.

    Check yourself

    1. Define population, community, habitat and ecosystem.
    2. Why can a pyramid of number be inverted when a biomass pyramid cannot?
    3. Explain why only about 10 % of energy passes between trophic levels.
    4. Name the four processes of the carbon cycle.
    5. (B) Which bacteria convert ammonia to nitrates, and which return nitrogen to the air?
    6. Why does carbon monoxide kill?
    7. Name the five greenhouse gases.
    8. Describe the eutrophication sequence in four steps.
    9. (B) Give two consequences of deforestation for the carbon cycle and two for the soil.

    Answers: 1 population — all organisms of one species in a habitat; community — all populations in a habitat; habitat — the place where organisms live; ecosystem — community plus its environment; 2 number counts individuals — one huge tree can feed many insects, inverting the shape — while biomass measures total mass, which always falls with each level; 3 energy is lost at each step through respiration (heat), movement, and egestion/excretion of uneaten parts; 4 photosynthesis, respiration, decomposition, combustion; 5 (B) nitrifying bacteria; denitrifying bacteria; 6 it binds to haemoglobin more strongly than oxygen, so blood carries less oxygen to tissues; 7 water vapour, carbon dioxide, nitrous oxide, methane, CFCs; 8 fertiliser runs into water → algal bloom → algae die and decomposers multiply → decomposers respire, using the oxygen, so fish and other organisms die; 9 (B) carbon: fewer trees photosynthesise, and burning/combaction releases stored carbon; soil: leaching of minerals and erosion without roots, with less evapotranspiration.

    Từ vựng
    English Tiếng Việt
    population/ˌpɒpjʊˈleɪʃn/ quần thể
    community/kəˈmjuːnɪti/ Quần xã
    habitat/ˈhæbɪtæt/ Môi trường sống
    ecosystem/ˈiːkəʊsɪstəm/ Hệ sinh thái
    abiotic/ˌæbɪˈɒtɪk/ Yếu tố phi sinh học
    biotic/baɪˈɒtɪk/ Yếu tố sinh học
    producer/prəˈdjuːsə/ Nhà sản xuất
    primary consumer/ˈpraɪməri kənˈsuːmə/ Tiêu thụ cấp một
    decomposer/ˌdiːkəmˈpəʊzə/ Nhà phân giải
    respiration/ˌrespɪˈreɪʃn/ hô hấp
    decomposition/ˌdiːkɒmpəˈzɪʃn/ Phân hủy
    combustion/kəmˈbʌstʃn/ Đốt cháy
    greenhouse gas/ˈɡriːnhaʊs ɡæs/ Khí nhà kính
    eutrophication/ˌjuːtrəfɪˈkeɪʃn/ Tăng dưỡng chất
    biodiversity/ˌbaɪəʊdaɪˈvɜːsɪti/ Đa dạng sinh học
  • 5

    5 · Use of biological resources

    Chương trình học sắp ra mắt

    Tài liệu

    English

    Using life to feed and to heal

    Bread rises, yoghurt thickens, insulin saves lives — all products of organisms put to work. This last section covers how humans increase yields (glasshouses, fertiliser, pest control), grow micro-organisms at scale (fermenters), and change organisms deliberately: selective breeding, genetic modification and cloning.

    Edexcel International GCSE Biology 4BI1, Section 5 (statements 5.1–5.20B) completes the course. The B-suffixed statements (fish farming, micropropagation, mammal cloning) are Biology-only.

    Food production

    Crop plants. Glasshouses and polythene tunnels trap heat and shelter crops, letting farmers control light, temperature, CO₂ and water; raising CO₂ and temperature toward the optimum lifts the photosynthesis rate and yield. Fertilisers replace mineral ions (nitrate for amino acids, magnesium for chlorophyll) the soil loses with each harvest. Pest control: pesticides kill pests quickly and completely but risk bioaccumulation 生物累积, harming other species and leaving residues; biological control 生物防治 (introducing a pest's predator) is self-sustaining and specific but slow and less controllable if the control species itself spreads.

    Micro-organisms. Yeast 酵母 ferments sugar: anaerobically it produces carbon dioxide (which raises bread) and ethanol; Lactobacillus converts milk sugar to lactic acid, thickening yoghurt. An industrial fermenter 工业发酵罐 keeps micro-organisms at their optimum: aseptic precautions (no contamination), nutrients, optimum temperature and pH, oxygenation (air supply for aerobic cultures) and agitation (stirring spreads heat and nutrients evenly).

    An industrial fermenter with nutrient and sterile-air inlets, stirrer, cooling jacket, probes and a harvest pipe.

    (B) Fish farming provides protein efficiently: maintain water quality, control predation (intraspecific — among the fish — and interspecific), control disease, remove waste, control feeding quality and frequency, and selectively breed fast-growing strains.

    Selective breeding

    Choose parents with the desired characteristics → breed them → select the best offspring → repeat over generations. It develops plants with higher yield, disease resistance or hardiness, and animals with more meat, milk or docility — but it narrows the gene pool, increasing vulnerability to disease, and takes many generations.

    Genetic modification (genetic engineering)

    Restriction enzymes 限制性内切酶 cut DNA at specific sites; ligase 连接酶 joins pieces of DNA together. A plasmid 质粒 (or a virus) acts as a vector 载体: the human insulin gene is cut out, inserted into a opened plasmid, and the recombinant DNA is taken up by bacteria, which multiply in a fermenter producing human insulin. GM plants can resist pests or herbicides or make more food. An organism receiving genes from a different species is transgenic 转基因.

    Genetic engineering of insulin in four steps: cut the gene, insert into a plasmid, return the vector to a bacterium, harvest insulin from the fermenter.

    Cloning (B)

    Micropropagation 微繁殖 (tissue culture): a small explant 外植体 is grown in vitro 体外 on a nutrient medium with growth hormones, producing genetically identical plantlets — commercial quantities of plants with desirable characteristics, disease-free and fast. Mammal cloning: a diploid nucleus from a mature cell is inserted into an enucleated egg cell (its own nucleus removed); the cell divides into an embryo placed in a surrogate — Dolly the sheep. Cloned transgenic animals can produce human proteins in their milk.

    Check yourself

    1. Give two ways a glasshouse raises crop yield.
    2. State one advantage and one disadvantage of biological control.
    3. Why does Lactobacillus thicken milk?
    4. List the five conditions a fermenter maintains.
    5. (B) Name two methods of controlling predation in fish farming.
    6. Give two drawbacks of selective breeding.
    7. Name the enzyme that cuts DNA and the one that joins it.
    8. What is a vector in genetic engineering?
    9. Explain why bacteria with the human insulin gene make useful medicine.
    10. (B) Outline the stages of cloning a mammal.

    Answers: 1 Traps heat near the optimum; CO₂, light and water controlled (any two); 2 Advantage — self-sustaining, no residues; disadvantage — slow, and the control species may spread; 3 It converts lactose to lactic acid, which coagulates the milk protein; 4 aseptic conditions, nutrients, optimum temperature and pH, oxygenation, agitation; 5 (B) net cages against interspecific predators; lower stocking density against intraspecific; 6 narrows the gene pool, so disease spreads easily; takes many generations.

    Answers continued: 7 Restriction enzymes cut; ligase joins; 8 a plasmid or virus carrying recombinant DNA into a cell; 9 they multiply fast in a fermenter, secreting human insulin — safe and producible at scale; 10 (B) Diploid nucleus from a mature cell → enucleated egg → divides into an embryo → implanted in a surrogate.

    Từ vựng
    English Tiếng Việt
    yeast/jiːst/ men
    industrial fermenter Lò lên men công nghiệp
    transgenic Biến đổi gen
    biological control/ˌbaɪəˈlɒdʒɪkl kənˈtrəʊl/ Kiểm soát sinh học
    bioaccumulation/ˌbaɪəʊəˌkjuːmjʊˈleɪʃn/ Tích lũy sinh học
    plasmid/ˈplæzmɪd/ Plasmid
    vector/ˈvektə/ véc-tơ
    ligase/ˈlɪɡeɪs/ ligase
    restriction enzyme enzim giới hạn
    micropropagation nhân giống vi mô
    explant mô mang
    in vitro ngoài cơ thể sống

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